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Tuesday, August 21, 2018

For a disinfectant to be effective the following factors are to be considered


   For a disinfectant to be effective the following factors are to be considered:

ü   Nature of what is to be disinfected
ü   Number of microorganisms and time (the higher the number the longer the time)
ü   Resistance of microorganisms
ü   Concentration used
ü   Kind of surface smooth or rough (rough requires longer time)
ü   Temperature and exposure time in relation to specific items
ü   Presence of organic materials

               Selection Criteria for Disinfectants
ü   Whether bactericidal or bacterial static
ü   Rapid activity
ü   Non corrosive
ü   Cost effectiveness and availability
ü   Stable when in contact with organic matter
ü   Active against a wide range of microorganisms
ü   Not damaging to instruments
ü   Easily biodegradable and less corrosive to the sewage system
ü   Less volatile and non toxic when it enters the atmosphere


Ø   When someone is reading manufacturer’s instructions before acquiring antiseptics and disinfectants for use, the following are things to note;
ü   Expiry date
ü   Label of container (well labeled with correct generic name of the disinfectant)
ü   Cover should explain the type of agent and not be torn
ü   Instructions on how to dilute (if not followed can damage instruments or equipment)
ü   Cautions of use

               Storage and Dispensing Conditions for Disinfectants
v   Accepted by the government
v   On disposal should not be hazardous to the community
v   Supply in small quantity, easy to handle
v   Establish schedule for preparing solution in small quantities for daily use
v   Cover container to prevent evaporation and contamination
v   Ensure container is labeled and read manufacture safety data sheet
v   Wash reusable containers well
v   Store in a cool and safe place

               Products That Should Not Be Used as Disinfectants
ü   Many antiseptic solutions are used incorrectly as disinfectants
ü   Although antiseptics (sometimes called ‘skin disinfectants’) are adequate for cleansing skin before surgical procedures, they are not appropriate for disinfecting surgical instruments
ü   They do not reliably destroy bacteria, viruses or endospores.
ü   For example Savlon (chlorhexidine gluconate with or without cetrimide), which is readily available worldwide, is often mistakenly used as a disinfectant


Ø   Antiseptics that should not be used as disinfectants:
ü   Acridine derivatives (e.g. gentian or crystal violet)
ü   Cetrimide (e.g. Cetavlon®)
ü   Chlorhexidine gluconate and cetrimide in various concentrations (e.g. Savlon)
ü   Chlorhexidine gluconate (e.g. Hibiscrub, Hibitane)
ü   Chlorinated lime and boric acid (e.g., Eusol®)
ü   Chloroxylenol in alcohol (e.g. Dettol)
ü   Hexachlorophene (e.g. pHisoHex)
ü   Mercury compounds

v   Mercury solutions (such as mercury laurel), although low-level disinfectants, cause birth defects and are too toxic to use as either disinfectants or antiseptics
v   Other products frequently used to disinfect equipment are 1–2% phenol (e.g. Phenol®),5% carbolic acid (Lysol®) and benzalkonium chloride, a quaternary ammonium compound (Zephiran®)
v   These are low-level disinfectants and should be used only to decontaminate environmental surfaces (e.g. floors or walls)


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